<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2024 Workiva-->
<!--r:91a911da-b03a-4128-899a-69f782cd8c0e,g:438f4dab-851e-4dad-937e-5a3a985bb2f9-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://si-bone.com/role/Cover" xlink:type="simple" xlink:href="sibn-20240226.xsd#Cover"/>
  <link:presentationLink xlink:role="http://si-bone.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_975f8890-d1e4-41e4-88f7-1787ccb88fed" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_DocumentType_975f8890-d1e4-41e4-88f7-1787ccb88fed" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_caf1cd83-0475-43f9-86d2-aac334e6b9d6" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_DocumentPeriodEndDate_caf1cd83-0475-43f9-86d2-aac334e6b9d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_fd158880-59e7-4d2d-8cc3-19a4573d7900" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityRegistrantName_fd158880-59e7-4d2d-8cc3-19a4573d7900" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_68e76abc-d19b-4af9-a080-06d383e4a073" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityCentralIndexKey_68e76abc-d19b-4af9-a080-06d383e4a073" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_dc5e2201-1292-4cdb-b796-1b653ea9d917" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_AmendmentFlag_dc5e2201-1292-4cdb-b796-1b653ea9d917" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_a7f7dc9a-cbf7-45a6-aaa5-bbebfb90d99a" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityIncorporationStateCountryCode_a7f7dc9a-cbf7-45a6-aaa5-bbebfb90d99a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_57e866c1-1380-436b-9f7d-1e67ccfdff6d" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityFileNumber_57e866c1-1380-436b-9f7d-1e67ccfdff6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_fa5f8d97-66bc-492a-b17d-f401e7c66302" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityTaxIdentificationNumber_fa5f8d97-66bc-492a-b17d-f401e7c66302" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_b5e15708-31fb-4f3b-9fbc-9534eaa3af18" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityAddressAddressLine1_b5e15708-31fb-4f3b-9fbc-9534eaa3af18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_a1668eba-2833-4852-9175-225ccffe0ba7" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine2"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityAddressAddressLine2_a1668eba-2833-4852-9175-225ccffe0ba7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_cbfc055b-a557-41e1-aca4-a6b5bea4d9b1" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityAddressCityOrTown_cbfc055b-a557-41e1-aca4-a6b5bea4d9b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_ddbadc4e-0331-4ad8-ad0b-70637ab38aae" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityAddressStateOrProvince_ddbadc4e-0331-4ad8-ad0b-70637ab38aae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_77ceb5f5-658d-42fd-8634-506377797372" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityAddressPostalZipCode_77ceb5f5-658d-42fd-8634-506377797372" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_2b1fcbe0-fe82-4cc4-a350-23d6f56dce6a" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_CityAreaCode_2b1fcbe0-fe82-4cc4-a350-23d6f56dce6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_4372742e-f0ac-4b91-b866-ce2af4a20ce1" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_LocalPhoneNumber_4372742e-f0ac-4b91-b866-ce2af4a20ce1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_dfb446b6-2a4b-4c25-9c96-df3470479dfc" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_WrittenCommunications_dfb446b6-2a4b-4c25-9c96-df3470479dfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_8468ef99-5a73-4727-8560-2b34a44e48ec" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_SolicitingMaterial_8468ef99-5a73-4727-8560-2b34a44e48ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_22f9b75d-203f-4b86-8e13-939950f01438" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_PreCommencementTenderOffer_22f9b75d-203f-4b86-8e13-939950f01438" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_0627fc25-bab7-49e1-81a1-d3520875194b" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_0627fc25-bab7-49e1-81a1-d3520875194b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_74e2a79e-d079-43cc-9731-c379d2190f68" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_Security12bTitle_74e2a79e-d079-43cc-9731-c379d2190f68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_d76bda5a-6ffa-498c-8636-2c8ed0db5b3e" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_TradingSymbol_d76bda5a-6ffa-498c-8636-2c8ed0db5b3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_89e4fd53-4edb-4d8d-a11a-bf630dd7b51e" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_SecurityExchangeName_89e4fd53-4edb-4d8d-a11a-bf630dd7b51e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_2e693e67-ce60-4163-85b8-ada1a0d020a7" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_6a23cb04-15e3-47f3-bae1-1c9aa8294418" xlink:to="loc_dei_EntityEmergingGrowthCompany_2e693e67-ce60-4163-85b8-ada1a0d020a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
