<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2025 Workiva-->
<!--r:068f5d66-91ba-45cd-a8c2-c78293f3c97c,g:1b1aa96f-a9c9-4fe5-9631-7c63b2346b84-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://si-bone.com/role/Cover" xlink:type="simple" xlink:href="sibn-20251106.xsd#Cover"/>
  <link:presentationLink xlink:role="http://si-bone.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_a924569c-1d07-4d1c-b822-cd4833bcd52a" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_DocumentType_a924569c-1d07-4d1c-b822-cd4833bcd52a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_3aa9d74f-6a30-4343-8469-5a87da1e27dc" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_DocumentPeriodEndDate_3aa9d74f-6a30-4343-8469-5a87da1e27dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_7fb6daca-85f2-4563-ae19-926dfc6362e9" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityRegistrantName_7fb6daca-85f2-4563-ae19-926dfc6362e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_63cb6e7f-0e86-4d04-9508-d1ca91db37cd" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityCentralIndexKey_63cb6e7f-0e86-4d04-9508-d1ca91db37cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_9ccd5676-d2ce-4baa-859e-8f9482b453fa" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_AmendmentFlag_9ccd5676-d2ce-4baa-859e-8f9482b453fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_65b36434-dd42-41e8-953d-0802332dad3a" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityIncorporationStateCountryCode_65b36434-dd42-41e8-953d-0802332dad3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_f73b65a5-ec45-4f4d-beb0-42d21f8ad88b" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityFileNumber_f73b65a5-ec45-4f4d-beb0-42d21f8ad88b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_48dd9708-83eb-4f68-9f04-9f422282a4bc" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityTaxIdentificationNumber_48dd9708-83eb-4f68-9f04-9f422282a4bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_e441c3d8-2870-4422-9fae-777559fe6dfd" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityAddressAddressLine1_e441c3d8-2870-4422-9fae-777559fe6dfd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_2a11aa11-1837-4af7-888f-30f06b36e1e4" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressAddressLine2"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityAddressAddressLine2_2a11aa11-1837-4af7-888f-30f06b36e1e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_1559032d-6183-49ba-94f1-98334ee7e50a" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityAddressCityOrTown_1559032d-6183-49ba-94f1-98334ee7e50a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_5cdcd436-6cf7-4cbc-9f5f-4f87305143aa" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityAddressStateOrProvince_5cdcd436-6cf7-4cbc-9f5f-4f87305143aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_70c81da4-c11b-41ad-acc4-9b735b9229ea" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityAddressPostalZipCode_70c81da4-c11b-41ad-acc4-9b735b9229ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_732dbba5-0227-4a32-a2e5-03c3710b54c3" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_CityAreaCode_732dbba5-0227-4a32-a2e5-03c3710b54c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_1a6c6f29-7544-42a7-b7a7-9614d7e12892" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_LocalPhoneNumber_1a6c6f29-7544-42a7-b7a7-9614d7e12892" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_9e898dd8-2ad5-401b-8372-c7340cffb376" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_WrittenCommunications_9e898dd8-2ad5-401b-8372-c7340cffb376" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_f8fbc11c-5a51-4986-b82c-4028bf4c9cc3" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_SolicitingMaterial_f8fbc11c-5a51-4986-b82c-4028bf4c9cc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_65719786-e626-4a48-a323-d9734c12fe5d" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_PreCommencementTenderOffer_65719786-e626-4a48-a323-d9734c12fe5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_7351250b-aaaa-496f-aa07-fd3e1c8bda77" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_7351250b-aaaa-496f-aa07-fd3e1c8bda77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_afd01a9d-a319-450e-85eb-694e06c85071" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_Security12bTitle_afd01a9d-a319-450e-85eb-694e06c85071" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_60edfd16-bb89-4883-b53e-854228b9fbcd" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_TradingSymbol_60edfd16-bb89-4883-b53e-854228b9fbcd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_bbaaee5b-f5b7-4c9b-b350-40567d0ebce4" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_SecurityExchangeName_bbaaee5b-f5b7-4c9b-b350-40567d0ebce4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_14914f35-c04a-4bb5-9036-6cea5dca5d2f" xlink:href="https://xbrl.sec.gov/dei/2025/dei-2025.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_d3241cc7-38be-4e9c-9380-330e46a92d06" xlink:to="loc_dei_EntityEmergingGrowthCompany_14914f35-c04a-4bb5-9036-6cea5dca5d2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
