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  <xs:element id="sibn_OperatingLossCarryforwardsLimited" abstract="false" name="OperatingLossCarryforwardsLimited" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_RevenueRecognitionStandardPaymentTerms" abstract="false" name="RevenueRecognitionStandardPaymentTerms" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="sibn_SocialSecurityTaxEmployerDeferralCARESAct" abstract="false" name="SocialSecurityTaxEmployerDeferralCARESAct" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_OptionsTrancheOneMember" abstract="true" name="OptionsTrancheOneMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="sibn_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationVestingOfEarlyExercisedStockOptions" abstract="false" name="AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationVestingOfEarlyExercisedStockOptions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_WarrantsIssuedNovemberTwentySixthTwentyFourteenMember" abstract="true" name="WarrantsIssuedNovemberTwentySixthTwentyFourteenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="sibn_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisePriceAsPercentOfFairMarketValueForIndividualOwningMoreThanTenPercentOfOutstandingShares" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisePriceAsPercentOfFairMarketValueForIndividualOwningMoreThanTenPercentOfOutstandingShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="sibn_SVBAmendedTermLoanMember" abstract="true" name="SVBAmendedTermLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="sibn_LineOfCreditFacilityContingentCommitmentFeeAmount" abstract="false" name="LineOfCreditFacilityContingentCommitmentFeeAmount" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_EmployeeStockPurchasePlanSharesMember" abstract="true" name="EmployeeStockPurchasePlanSharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="sibn_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisePriceAsPercentOfFairMarketValue" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisePriceAsPercentOfFairMarketValue" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="sibn_CommonStockWarrantsMember" abstract="true" name="CommonStockWarrantsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="sibn_WarrantsOutstandingFairValueOnDateOfIssuanceOrConversion" abstract="false" name="WarrantsOutstandingFairValueOnDateOfIssuanceOrConversion" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_MarketableSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" abstract="false" name="MarketableSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_ConstructionInProgressSantaClaraLeaseMember" abstract="true" name="ConstructionInProgressSantaClaraLeaseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="sibn_DefinedContributionPlanEmployerMatchingContributionMaximumAmountPerEmployee" abstract="false" name="DefinedContributionPlanEmployerMatchingContributionMaximumAmountPerEmployee" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_WarrantsIssuedJulyTwentySecondTwentyThirteenMember" abstract="true" name="WarrantsIssuedJulyTwentySecondTwentyThirteenMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="sibn_PrepaymentPenaltyAndLenderFeesInExtinguishmentOfDebt" abstract="false" name="PrepaymentPenaltyAndLenderFeesInExtinguishmentOfDebt" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="sibn_RelatedPartyTransactionTermOfAgreement" abstract="false" name="RelatedPartyTransactionTermOfAgreement" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
</xs:schema>
